Person, Text, Face


The Research and Development team at Foundation Medicine is constantly pushing the envelope to transform cancer care.

Watch the video above to see how each member has the chance to make a real impact. 


Scientist I, Assay Development

  • Cambridge, Massachusetts, United States
  • Full Time

About the Job

The Scientist I, Assay Development supports the late-stage development and optimization of next generation sequencing (NGS) based assays in our clinical labs. Leveraging strong working knowledge of molecular biology, the incumbent in this position partners closely with other scientists and stakeholders cross functionally on high throughput automation and advancing NGS. The Scientist I prepares and analyzes human specimens, conducts laboratory experiments within guidelines and operates and maintains complex scientific equipment, such as high throughput liquid handlers. Additionally, the Scientist I evaluates and summarizes results, contributes to reports, presents data, and remains up-to-date with current publications relative to methods and techniques within relevant areas of research to leverage and integrate these.

Key Responsibilities

  • Independently execute specialized and complex molecular biology techniques, including NGS workflows.
  • Collaborate with molecular biologists, computational scientists and regulatory scientists to support the feasibility and development of clinical oncology NGS diagnostic assays.
  • Design and conduct required feasibility and development and validation work, and help to draft standard operating protocols.
  • Operate complex laboratory equipment such as laboratory automation equipment.
  • Utilize data analysis interpretation and troubleshooting to identify methods to optimize assay features.
  • Author detailed, accurate, and accessible records of experimental data and protocols, plans and reports within the Quality Management System as needed.
  • Prepare reports and presentations to communicate results in group meetings.
  • Train and mentor research assistants and/or research associates on optimal processes and standard operating procedures.
  • Other duties as assigned.


Basic Qualifications

  • Bachelor’s Degree in Molecular Biology or a related life science fields
  • 3+ years of experience in life science research experience in industry, a clinical research organization, or a hospital

Preferred Qualifications

  • Advanced Degree (Master’s Degree+) in Molecular Biology or a related life science field
  • Extensive experience with molecular biology techniques and an understanding of the practices and principals of NGS, including DNA-seq, NGS library preparation and target-enrichment
  • Experience developing, implementing and supporting high complexity clinical assays
  • Experience within the following regulated environments: Food and Drug Administration – Quality System Regulation, Clinical Laboratory Improvements Amendments, International Organization for Standardization and CAP, and in writing standard operating procedures, validation protocols and data reports within these environments
  • A “results-oriented attitude”, demonstrated through a history of meeting individual and collaborative project deadlines
  • Scientific thought process and understanding of assay parameters illustrating approaches to problem solving to inform assay troubleshooting and or optimization.
  • Good interpersonal skills that include excellence in written communication, oral communication, collaboration, and problem solving with other departments and colleagues
  • Understanding of HIPAA and the importance of patient data privacy
  • Commitment to reflect FMI’s values: Passion, Patients, Innovation, and Collaboration



Please be aware that Foundation Medicine mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.


About Foundation Medicine

Foundation Medicine, Inc. (FMI) began with an idea—to simplify the complex nature of cancer genomics, bringing cutting-edge science and technology to everyday cancer care. Our approach generates insights that help doctors match patients to more treatment options and helps accelerate the development of new therapies. Foundation Medicine is the culmination of talented people coming together to realize an important vision, and the work we do every day impacts real lives.

Confidence, or the belief that we need to check every box before applying for a job, can sometimes hold us back from going after a role that inspires us. At Foundation Medicine there's no such thing as the 'perfect' applicant, and our company is a place where every employee can make an impact and continue to grow whatever background they may have or path they may have taken. So, as long as you meet the basic qualifications for a role, please apply if you see a position that would make you excited to come into Foundation Medicine every day and help us transform cancer care.

Apply Now

Internal applicants, please use your FMI email address.

Please let me know about more jobs like this

Not You?

Thank you

Recommended Jobs

Sr. Mgr, BioPharma Analytics Lead

Biopharma Business Operations and Customer Experience 102419 United States United States Biopharma
About the Job The Analytics Lead is a key member of the BioPharma Business Operations & Customer Experience team. This role is responsible for leading the development and execution of analyses to deliver timely and actionable insights that drive...

Dir, Commercial Programs

Field Business Enablement 102418 United States United States Commercial
About the Job The Director, Commercial Programs owns achievement of strategic objectives and key results across the entire range of FMI products, services adoption, and their relationship to customer retention and sales growth. The role works cl...

Product Manager

Engineering 102417 Boston Massachusetts United States Seaport Blvd., Boston, Massachusetts, United States Technology
About the Job The Insights Generation (IG) group sits at a critical juncture between our labs and our end users. IG is responsible for generating the reports and data that are ultimately delivered to our partners and physicians. The Product Mana...

Intern, Software Engineer - Computational Biology

Computational Biology 102412 Cambridge Massachusetts United States Cambridge, Massachusetts, United States R&D
About the Job Foundation Medicine is seeking a motivated intern to join our Software Engineering team. The Intern will contribute to the development of software and data systems used to solve problems in genomics, transcriptomics, and proteomics...

Send to a friend

Not You?

Thank you for sending this job to your friend.

Clothing, Apparel, Person, Scarf, Finger, Plant, Sitting, Female
Lab, Apparel, Clothing, Person, Scientist, Coat, Lab Coat

Foundation Medicine is proud to be an Equal Opportunity and Affirmative Action employer and considers all qualified applicants for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin. Further, qualified applicants will not be discriminated against on the basis of disability or protected veteran status. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. See also FMI’s EEO Statement and EEO is the Law and Supplement. If you have a disability or special need that requires accommodation, please let us know by completing this form.  (EOE/AAP Employer)

To all recruitment agencies: Foundation Medicine does not accept agency resumes. Please do not forward resumes to our jobs alias, Foundation Medicine employees or any other organization location. Foundation Medicine is not responsible for any fees related to unsolicited resumes.