About the Job
The Senior Automation Engineer is responsible for automating and scaling complex workflows and implementing processes for deployment in clinical laboratories at multiple sites. The position is involved in all aspects of assay automation development and instrument integration, from concept to requirements definition, method development, optimization, troubleshooting and validation. The role identifies problem areas and develops solutions to reduce Turn-Around-Time (TAT), increase sample processing capacity, and improve assay performance. The Senior Automation Engineer is involved in performing installation and operational qualifications of automation equipment, and is also responsible for generating the documents required for this activity. The position is part of the team responsible for the development and integration of automated systems to ensure efficient productivity of patient processing.
This is a regulated position and additional information may be available from QA on the qualifications for this role pertaining to regulatory guidelines.
• Develop and improve robust automated solutions utilizing liquid handlers and other laboratory automation equipment designed to remove bottlenecks, increase capacity and reduce TAT in FMI’s high throughput (24/7) Next Generation Sequencing lab.
• Program, optimize, verify, and implement new and/or improved methods on robotic liquid handling workstations and integrated robotic systems.
• Design and prototype components for integration of robotic systems through iterative improvements while working with scientists.
• Provide on-site technical support of automation platforms.
• Analyze workflows, identify bottlenecks, and develop solutions to improve efficiency, throughput, cost, and quality.
• Generate and maintain requirements and test plan documentation.
• Integrate instrument components and perform unit testing of instruments.
• Contribute to innovation of current and new assays’ workflows, technologies, and processes.
• Install, test, and control new versions of automated protocols on applicable instrumentation across labs and possibly across sites.
• Provide training and documentation for new or modified workflows to end users.
• Other duties as assigned.
• Bachelor’s Degree in Bioengineering, Biotechnology or a similar life science and 5+ years of related experience with high-throughput laboratory instrumentation; OR
• Master’s Degree in one of the fields specified above and 3+ years of relevant experience
• Previous experience working in a molecular diagnostics/clinical laboratory setting
• Experience working in a regulated environment (e.g. CLIA, CAP, ISO, GxP)
• Experience communicating and collaborating with internal and external colleagues and customers from diverse scientific, engineering, operational, and regulatory disciplines
• Experience with:
· Robotic liquid handlers from Hamilton, TECAN, Agilent Technologies, Dynamic Devices or Beckman Coulter
· Developing and implementing integrated robotic systems for use in a high throughput environment
· Developing, optimizing, and validating assays for use in a high throughput environment
· Standard molecular biology techniques such as nucleic acid isolation, purification and quantitation, bioanalyzer, DNA/RNA quantitation, qPCR or Next Generation Sequencing
• Knowledge of safety protocols in a laboratory setting
• Familiarity with streamlining workflows and developing automated laboratory processes and instrumentation systems, including collecting and documenting requirements, developing concepts, design, testing/validation, implementing, and training
• Ability to work as an individual as well as in a team environment
• Ability to work in a lab environment in the presence of chemicals and reagents
• Strong written and oral communication skill
Internal applicants, please use your FMI email address.
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