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The Research and Development team at Foundation Medicine is constantly pushing the envelope to transform cancer care.

Watch the video above to see how each member has the chance to make a real impact. 


Senior Research Associate, Product Development

  • Towne Centre Ct., San Diego, California, United States
  • Full Time

About the Job

Senior Research Associate (SRA) in the Companion Diagnostics (CDx)/Development Operations team supports the development of new NGS-based molecular diagnostics. This position will contribute to laboratory and documentation activities in collaboration with a cross-functional team to verify and validate product requirements, assay design, and assay performance. The SRA prepares DNA from human specimens and operates automated liquid handlers to conduct high-throughput NGS sequencing. Additionally, the SRA will participate in documentation of device performance protocols and reports and data presentation.

Key Responsibilities

• Prepare and isolates nucleic acid from oncology specimens (such as DNA/RNA extraction from FFPE tissue and blood samples).

• Perform standard molecular biology techniques (such as enzymatic manipulation of DNA and RNA).

• Perform specialized and complex experiments in such areas of Next Generation Sequencing.

• Operate complex laboratory equipment such as laboratory automation equipment.

• Maintain records of experimental procedures.

• Manage experimental data in a computer database (e.g. LIMS).

• Prepare reports and presentations to communicate results in group meetings.

• Train and mentor other team members on standard operating procedures.

• Participate in training sessions and workshops.

• Perform lab testing independently.

• Other duties as assigned.


Basic Qualifications

• Bachelor’s Degree in Molecular Biology or a related life science field and 1+ years of life science research experience in industry, a clinical research organization, or a hospital

• OR

• a Master’s Degree in Molecular Biology or a related life science field

Preferred Qualifications

• Master’s Degree in Molecular Biology or a related life science field

• Experience working with oncology specimens including Formalin-fixed, Paraffin-embedded (FFPE) tissue samples, blood, bone marrow

• Experience working with standard molecular biology techniques (nucleic acid isolation and analysis, Polymerase Chain Reaction (PCR), and enzymatic manipulation of DNA and RNA

• Demonstrate a good understanding of the practices and principals of NGS, including DNA-seq and RNA-seq protocols, and various target-enrichment approaches e.g. multiplex-PCR, hybrid selection

• Familiarity with liquid handling equipment such as Hamilton Star or Agilent Bravo

• Proficiency in Microsoft Office suite, particularly Word and Excel

• Demonstrated ability to effectively communicate, both written and verbal, scientific concepts, experimental plans, and results

• Experience in a Quality System Regulations (QSR) part 820 or CLIA/CAP compliant laboratory (e.g. experience in GDP, non-compliance documentation)

• Understanding of HIPAA and the importance of patient data privacy

• Commitment to reflect FMI’s values: Passion, Patients, Innovation, and Collaboration


Please be aware that Foundation Medicine mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.


About Foundation Medicine

Foundation Medicine, Inc. (FMI) began with an idea—to simplify the complex nature of cancer genomics, bringing cutting-edge science and technology to everyday cancer care. Our approach generates insights that help doctors match patients to more treatment options and helps accelerate the development of new therapies. Foundation Medicine is the culmination of talented people coming together to realize an important vision, and the work we do every day impacts real lives.

Confidence, or the belief that we need to check every box before applying for a job, can sometimes hold us back from going after a role that inspires us. At Foundation Medicine there's no such thing as the 'perfect' applicant, and our company is a place where every employee can make an impact and continue to grow whatever background they may have or path they may have taken. So, as long as you meet the basic qualifications for a role, please apply if you see a position that would make you excited to come into Foundation Medicine every day and help us transform cancer care.

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Internal applicants, please use your FMI email address.

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Foundation Medicine is proud to be an Equal Opportunity and Affirmative Action employer and considers all qualified applicants for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin. Further, qualified applicants will not be discriminated against on the basis of disability or protected veteran status. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. See also FMI’s EEO Statement and EEO is the Law and Supplement. If you have a disability or special need that requires accommodation, please let us know by completing this form.  (EOE/AAP Employer)

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