Person, Text, Face


The Research and Development team at Foundation Medicine is constantly pushing the envelope to transform cancer care.

Watch the video above to see how each member has the chance to make a real impact. 


Sr Research Associate, Assay Development

  • Cambridge, Massachusetts, United States
  • Full Time

About the Job

The Senior Research Associate (SRA), Assay Development support late-stage development, design and laboratory systems integration of Next Generation Sequencing (NGS)-based molecular diagnostic assays for internal and external research projects. As a senior-level position, the incumbent is responsible for leveraging additional years of experience and/or education for a more advanced level of analysis and research activities. The SRA prepares and analyzes human specimens, conducts laboratory experiments within guidelines and operates and maintains complex scientific equipment, such as high throughput liquid handlers. Additionally, the SRA evaluates and summarizes results, prepares reports, presents data, and remains up-to-date with current publications relative to methods and techniques within relevant areas of research to leverage and integrate these.

Key Responsibilities

  • Prepare and isolate nucleic acid from oncology specimens (such as DNA/RNA extraction from FFPE tissues and blood samples).
  • Perform standard molecular biology techniques (such as enzymatic manipulation of DNA and RNA).
  • Perform specialized and complex experiments in such areas of Next Generation Sequencing.
  • Operate complex laboratory equipment such as high throughput liquid handlers and Illumina sequencers.
  • Support the timely processing and reporting of oncology samples to internal and external collaborators.
  • Manage experimental data in a computer database (e.g. LIMS).
  • Analyze and troubleshot QC results to ensure quality of products.
  • Maintained proper QC/QA documentation.
  • Develop and follow SOPs.
  • Train and mentor other team members on standard operating procedures.
  • Participate in training sessions and workshops.
  • Other duties as assigned.


Basic Qualifications

  • Bachelor's Degree in Molecular Biology or a related life science field and 1+ year of life science research experience in industry, a clinical research organization, or a hospital
  • OR
  • Master’s degree in Molecular Biology or a related life science field

Preferred Qualifications

  • Master’s Degree in Molecular Biology or a related life science field
  • Experience working with typical oncology specimens including Formalin-fixed, Paraffin-embedded (FFPE) tissue samples, blood, bone marrow
  • Experience working with standard molecular biology techniques (nucleic acid isolation and analysis, Polymerase Chain Reaction (PCR), qPCR, and enzymatic manipulation of DNA and RNA)
  • Experience with high throughput automation and liquid handling equipment’s (such as Hamilton Star, KingFisher)
  • Demonstrate good understanding of the practices and principals of NGS, including DNA-seq and RNA-seq protocols, and various target-enrichment approaches e.g. multiplex-PCR, hybrid selection
  • Demonstrated ability to effectively communicate, both written and verbal, scientific concepts, experimental plans, and results
  • Proficiency in Microsoft Office suite, particularly Word, Power Point, Excel
  • Proficiency in data visualization and statistical software (such us, JMP)
  • Understanding of HIPAA and importance of privacy of patient data
  • Commitment to reflect FMI’s values: passion, patients, collaboration, and innovation



Please be aware that Foundation Medicine mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.


About Foundation Medicine

Foundation Medicine, Inc. (FMI) began with an idea—to simplify the complex nature of cancer genomics, bringing cutting-edge science and technology to everyday cancer care. Our approach generates insights that help doctors match patients to more treatment options and helps accelerate the development of new therapies. Foundation Medicine is the culmination of talented people coming together to realize an important vision, and the work we do every day impacts real lives.

Confidence, or the belief that we need to check every box before applying for a job, can sometimes hold us back from going after a role that inspires us. At Foundation Medicine there's no such thing as the 'perfect' applicant, and our company is a place where every employee can make an impact and continue to grow whatever background they may have or path they may have taken. So, as long as you meet the basic qualifications for a role, please apply if you see a position that would make you excited to come into Foundation Medicine every day and help us transform cancer care.

Apply Now

Internal applicants, please use your FMI email address.

Please let me know about more jobs like this

Not You?

Thank you

Recommended Jobs

Sr. Director, Area Sales - West

Commercial Execution 102359 United States United States Commercial
About the Job The Senior Director - Area Sales is a field-based role with direct customer engagement that leverages industry experience to identify, develop, and pursue customer opportunities and foster, build, and maintain relationships with cu...

Sr. Director, Area Sales - North East

Commercial Execution 102358 United States United States Commercial
About the Job The Senior Director - Area Sales is a field-based role with direct customer engagement that leverages industry experience to identify, develop, and pursue customer opportunities and foster, build, and maintain relationships with cu...

Senior Manager, Quality Assurance - Lab Ops

Quality Assurance 102317 Cambridge Massachusetts United States Cambridge, Massachusetts, United States Operations
About the Job The Senior Manager in the LabOps Quality Assurance department is an integral part of a highly productive team overseeing GxP activities at the FMI Laboratory site with close collaboration with the Laboratory Operations (LabOps) tea...

Sr Project Manager

ctDNA-Research and Early Development 102355 San Diego. Cambridge California. Massachusetts United States Torreyana Road, San Diego, California, United States. Cambridge, Massachusetts, United States R&D
About the Job The Senior Project Manager, Early Detection is responsible for the planning and execution of new biopharma clinical product development projects and/or lab expansion projects, as well as other business critical initiatives. The rol...

Send to a friend

Not You?

Thank you for sending this job to your friend.

Clothing, Apparel, Person, Scarf, Finger, Plant, Sitting, Female
Lab, Apparel, Clothing, Person, Scientist, Coat, Lab Coat

Foundation Medicine is proud to be an Equal Opportunity and Affirmative Action employer and considers all qualified applicants for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin. Further, qualified applicants will not be discriminated against on the basis of disability or protected veteran status. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. See also FMI’s EEO Statement and EEO is the Law and Supplement. If you have a disability or special need that requires accommodation, please let us know by completing this form.  (EOE/AAP Employer)

To all recruitment agencies: Foundation Medicine does not accept agency resumes. Please do not forward resumes to our jobs alias, Foundation Medicine employees or any other organization location. Foundation Medicine is not responsible for any fees related to unsolicited resumes.